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Play Health

Perimenopause health platform redefining women's midlife care

Play Health is a perimenopause health platform redefining midlife care for women.  Despite affecting over 30 million women in the U.S. alone, perimenopause remains one of the most overlooked stages in women’s health. The science is complex, the data is sparse, and most existing solutions are either too generic or too narrow to deliver meaningful insights. Women are left navigating life-altering symptoms with little guidance and few tools built specifically for them. Play Health changes that. We combine personalized tracking, at-home hormone testing, and AI-driven analytics to deliver actionable, data-first insights, and build the most advanced longitudinal dataset in perimenopause to date. This unlocks improved health today and enables the discovery of new diagnostics, therapeutics, and standards of care for tomorrow. Play Health is led by successful, second-time, YC founders Andrea Mazzocchi and Ian Miller, with an exit and a unicorn between them.
Active Founders
Andrea Mazzocchi
Andrea Mazzocchi
Founder
Co-founder & CEO at Play Health - a perimenopause care platform to improve women's midlife health. Previously, research in tissue engineering, tumor microenvironments, cancer precision medicine. Was also CEO at Known Medicine (S20) which raised ~$8.2M and was ultimately acquired by Pathos AI in spring 2023.
Ian Miller
Ian Miller
Founder & CTO
Co-founder & CTO at Play Health - a perimenopause care platform to improve women's midlife health. Passionate about tech solutions for making people's lives better. Love working with cross-functional teams.
Company Launches
Play Health: Perimenopause Care Platform
See original launch post

TL;DR

Play Health’s Perimenopause Care Platform combines comprehensive symptom + cycle tracking, at-home hormone testing, and AI-driven content to give women actionable, personalized insights to help relieve symptoms and improve quality of life.

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https://www.youtube.com/watch?v=zzmHWl0jhfM

Why It Matters

Perimenopause is when women begin to experience hormonal changes and symptoms of menopause such as brain fog, mood shifts, and hot flashes, while still having their period. It can start in the mid-30s and last 10+ years.

Despite impacting 30M+ women in the U.S. alone, perimenopause remains one of the most overlooked stages in women’s health. The science is complex, the data is sparse, and existing solutions are either too generic or too narrow. Women are left navigating life-altering symptoms with little guidance and few tools.

Perimenopause care today is where fertility care was a decade ago: under-researched, under-funded, and urgently in need of innovation. Play Health is changing that.

Play Health’s Perimenopause Care Platform

  • Track what matters: cycle, symptoms, lifestyle, supplements, and therapeutics.
  • Test at home: perimenopause-specific hormone test, designed for real-world use.
  • Turn data into action: AI-powered personalized insights to relieve symptoms and support long-term health.

By combining personalized care today with a foundational dataset for tomorrow, Play Health is setting a new standard for women’s midlife health.

About Us

Play Health was founded by Andrea Mazzocchi, PhD and Ian Miller, second-time YC founders with a track record of building and scaling impactful companies.

  • Andrea previously served as CEO of Known Medicine (YC S20), leading its acquisition by Pathos AI in 2023.
  • Ian co-founded **Gecko Robotics (YC W16)**—now a unicorn—and later led automation and engineering at Known Medicine and Pathos.

Together, they bring deep technical and scientific expertise and a shared mission: to close the massive care gap in women’s health, starting with perimenopause.

Better perimenopause care today. Breakthrough science tomorrow.

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Play Health
Founded:2025
Batch:Fall 2025
Team Size:3
Status:
Active
Location:Boulder, CO
Primary Partner:Nicolas Dessaigne